We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry", said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveraging unique strengths in different geographies, East or West. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. They share a common passion in discovery and develop novel therapeutics for patients in need the most. 700 Technology Square, 5th Floor Cambridge, MA 02139 617.674.5100 However, PEM treatment also induced adenosine production, which inhibited T-cell responsiveness. Cancer Lett. ATB is funded by Anlong Venture, Bohe Angel Fund and Katai Capital. Yuanhua Ding - AllianThera Biopharma (ATB) | ChinaBio Partnering Forum 2022 Speaker Yuanhua Ding Founder and Chief Executive Officer at AllianThera Biopharma (ATB) Agenda Sessions Innovating for tomorrow, innovating for the world On Demand View Session Speakers at this event Prev Next Tina Elder Global General Manager EBD Group FDA panels loom for GSK and Biogen, with approval decisions due for Acadia and Biomarin. We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry", said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. Design Therapeutics. 12 Dana-Farber Cancer Institute, Boston, United States. Claim your Free Employer Profile. 2012 Oct;11(10):2149-57. doi: 10.1158/1535-7163.MCT-12-0195. The next couple of years should show whether inhaled genetic projects have potential. 252021500ESTAllianThera BiopharmaATBInsilicoMedicine PandaOmicsInsilico Medicine R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. Welcome to the Society for Clinical Trials (SCT). Epub 2012 Jul 25. Yamaoka T, Ohmori T, Ohba M, Arata S, Kishino Y, Murata Y, Kusumoto S, Ishida H, Shirai T, Hirose T, Ohnishi T, Sasaki Y. Mol Cancer Ther. Strategies to overcome acquired resistance to EGFR TKI in the treatment of non-small cell lung cancer. Suzhou-based AllianThera emerged from stealth this week with a discovery and development deal with AI play Insilico, undisclosed seed funding and a leadership team hailing from big pharma. MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. Please enable it to take advantage of the complete set of features! and transmitted securely. 2009 Jul;10(4):281-9. doi: 10.3816/CLC.2009.n.039. Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition - Add Awards Clin Transl Oncol. Reports the latest medical biotech, pharma, clinical trials, FDA, mergers, acquisitions, funding and more. official website and that any information you provide is encrypted Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients . Show more AllianThera Biopharma headquarters is in Suzhou, Jiangsu. The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. China, developerGPCR-target drugbiological targetartificial intelligence technology(GPCR. Advanced Search Title. alicia@thrustsc.com. -, DaSilva JO, Yang K, Surriga O, Nittoli T, Kunz A, Franklin MC, et al. Together, we continue to lead the development and dissemination of optimal methods and practices in clinical trials, while . But is the agency really stopping deals from happening? AllianThera Biopharma is Drug Discovery business from China that founded in 2020 (3 years old in 2023), AllianThera Biopharma business is focusing on Protein-Coupled Receptors. Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation. 2019 Oct;21(10):1287-1301. doi: 10.1007/s12094-019-02075-1. Sign in with Apple. As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovator drug. In an allogenic humanized mouse model, CD73 deletion enhanced immunogenicity of MET-amplified, EGFR-TKI-resistant cells, and PEM treatment promoted robust responses regardless of CD73 status. Suzhou, Jiangsu . ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture andKatai Capital. 2023 SignalHire.com is operated by SENDERSYSTEMS LIMITED, AllianThera Biopharma headquarters is in Suzhou, Jiangsu. The company's principal address is 11 Bantry Rd., Southborough . Mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors and a potential treatment strategy. Clin Cancer Res 2018;24:6195203. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. BioWorld Briefs Other news to note Coronavirus Design Therapeutics. AllianThera Biopharma. Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveraging unique strengths in different geographies, East or West. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Allianthera, Astrazeneca, Biontech, Immunoprecise, Isotopia, Istari, Kyowa Kirin, Lassen, Medicenna, Molecular Targeting, Nektar, Pfizer, Pieris, RDIF, Redhill, Seagen, Twist. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Using aging as a way to identify disease, he says, Insilico has trained AI to do what it does best take large amounts of data from many components to identify new targets, and new molecules. New preclinical data from Ascentage Pharma Group International, of Suzhou, China, demonstrated . Disclaimer. ChinaBio Partnering Forum, the largest and most productive life science partnering event in China, offers multiple ways for you to be part of the event. AllianThera Biopharma Overview Work Here? Suzhou, Jiangsu The cytosolic DNA-sensing cGAS-STING pathway in cancer. These data reveal that combined PEM and CD73 inhibition can co-opt tumor cell STING induction in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity. Polly Firs AllianThera Biopharma was founded in China. GT Biopharma, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of immuno-oncology therapeutic products based our proprietary TriKE NK cell . SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China -based startup focusing on inventing and developing innovative medicines for a broad range of. 9 Guanghua Road, Chaoyang District, Beijing. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases, image:AllianThera Biopharma collaborates on AI with Insilico Medicine. AllianThera Biopharma ledby ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. AllianThera Biopharma 5 jobs. However, STING activation was restrained by ectonucleosidase CD73, which is induced in MET-amplified, EGFR-TKI-resistant cells. Bethesda, MD 20894, Web Policies Osimertinib in untreated EGFR-mutated advanced non-small-cell lung cancer. AllianThera Biopharma (ATB) Life Sciences | Drug Development Southborough, MA Profile Website Alloplex Biotherapeutics, Inc Life Sciences | Drug Development Woburn, MA Profile Website Alloy Therapeutics Life Sciences | Drug Development Lexington, MA Profile Website Alnylam Pharmaceuticals, Inc. Life Sciences | Drug Development Cambridge, MA Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Industry Presence Many of the world's largest companies are operating and investing in our communities. Learn More Above is snippet of Google Trends for "Protein-Coupled Receptors" term, if you have problem loading the snippet, please visit here: Google Trend. This site needs JavaScript to work properly. Can your gut microbes tell you how old you really are? As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovative drug. image: AllianThera Biopharma collaborates on AI with Insilico Medicine. Efforts to enhance the immunogenicity of EGFR-mutated lung cancer have been unsuccessful to date. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. Pemetrexed (PEM), which is commonly used following EGFR-TKI treatment failure, was identified as an effective potentiator of STING-dependent TBK1-IRF3-STAT1 signaling in MET-amplified, EGFR-TKI-resistant cells. 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